Until recently, the clinical application of direct injection of a single sperm into the cytoplasm of an oocyte during IVF was not shown to be feasible. The demonstration of fertilization and live births by Palermo et al. in 1993 was the first successful application of ICSI. Since that time, ICSI has been performed extensively in multiple centers to treat patients with severe male factor infertility. To date, the success of ICSI procedures has been related to several factors: (1) the viability of the spermatozoon, (2) the quality of the oocyte, …

ICSI stands for Intro Cytoplasmic Sperm Injection. The whole technique was developed by researches of Brussels University and a science institution in St. Louis, US. The amazing thing about ICSI procedure is that men who were considered ultimately unable to fertilize have succeeded in it and the procedure implication worldwide has already resulted in more than 10,000 babies and perfectly physically, genetically and mentally babies they are. You or your spouse might be the one for ICSI procedure if you are closely familiar with one of the following cases.
The …

Intra-cytoplasmic sperm injection (ICSI) is a relatively new but well-established procedure first performed in 1992. The procedure was developed to help male factor infertility. The procedure involves injecting a single sperm into the cytoplasm of each egg using a fine glass needle. The first ICSI baby was reported in 1992. The ICSI has largely replaced the two previously developed procedures, PZD (partial zona dissection) and SUZI (subzonal insemination) because it achieves much higher fertilization rates.
The injection of immature sperm (spermatid) into the egg is not allowed in the UK because …

Male. Male patients with a low sperm count have poor chances to impregnate their partners by natural means. While insemination can improve these chances, if changes in the quality of sperm are severe, the G.I.F.T. procedure may be the best answer to the problem. As research in this area improves, success in the treatment of male infertility will be significantly improved. Right now, the success rate of G.I.F.T. procedures is significantly higher than that of conception of other means (IVF/ET or vaginal/cervical/intrauterine insemination).
Female. Women play a major role during conception. …

The success rate after GIFT is similar to that of in-vitro fertilization (IVF) treatment. Some specialists claim a higher success rate with GIFT compared to IVF.
 
                               Procedure             Live birth rate per embryo transfer cycle
                                        IVF                                                        31.0%
                                        ICSI                                                       28.6%
                                        GIFT                                                      24.5%
                                        ZIFT                                                      29.2%
  
Choosing between GIFT and IVF treatment? There are several points worth considering when selecting between gamete intra-Fallopian transfer (GIFT) and in-vitro fertilization (IVF). The GIFT procedure is simpler and usually less stressful to the couple than IVF. However GIFT requires healthy Fallopian tubes, while IVF can be performed …